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RHO binding to FAM65A regulates Golgi reorientation during cell migration

Directional cell migration involves reorientation of the secretory machinery. However, the molecular mechanisms that control this reorientation are not well characterised. Here, we identify a new Rho effector protein, named FAM65A, which binds to active RHOA, RHOB and RHOC. FAM65A links RHO proteins...

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Vydáno v:J Cell Sci
Hlavní autoři: Mardakheh, Faraz K., Self, Annette, Marshall, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201024/
https://ncbi.nlm.nih.gov/pubmed/27807006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.198614
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