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Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes
Vinculin is a highly conserved protein involved in cell adhesion and mechanotransduction, and both gain and loss of its activity causes defective cell behaviour. Here, we examine how altering vinculin activity perturbs integrin function within the context of Drosophila development. Whereas loss of v...
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| 出版年: | J Cell Sci |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201009/ https://ncbi.nlm.nih.gov/pubmed/27737911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.189878 |
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