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Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes

Vinculin is a highly conserved protein involved in cell adhesion and mechanotransduction, and both gain and loss of its activity causes defective cell behaviour. Here, we examine how altering vinculin activity perturbs integrin function within the context of Drosophila development. Whereas loss of v...

詳細記述

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書誌詳細
出版年:J Cell Sci
主要な著者: Maartens, Aidan P., Wellmann, Jutta, Wictome, Emma, Klapholz, Benjamin, Green, Hannah, Brown, Nicholas H.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201009/
https://ncbi.nlm.nih.gov/pubmed/27737911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.189878
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