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Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes
Vinculin is a highly conserved protein involved in cell adhesion and mechanotransduction, and both gain and loss of its activity causes defective cell behaviour. Here, we examine how altering vinculin activity perturbs integrin function within the context of Drosophila development. Whereas loss of v...
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| Опубликовано в: : | J Cell Sci |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists Ltd
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201009/ https://ncbi.nlm.nih.gov/pubmed/27737911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.189878 |
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