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Close Correlation of Monoamine Oxidase Activity with Progress of Alzheimer’s Disease in Mice, Observed by in Vivo Two-Photon Imaging

[Image: see text] Monoamine oxidases (MAOs) play an important role in Alzheimer’s disease (AD) pathology. We report in vivo comonitoring of MAO activity and amyloid-β (Aβ) plaques dependent on the aging of live mice with AD, using a two-photon fluorescence probe. The probe under the catalytic action...

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Publicat a:ACS Cent Sci
Autors principals: Kim, Dokyoung, Baik, Sung Hoon, Kang, Seokjo, Cho, Seo Won, Bae, Juryang, Cha, Moon-Yong, Sailor, Michael J., Mook-Jung, Inhee, Ahn, Kyo Han
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5200925/
https://ncbi.nlm.nih.gov/pubmed/28058286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00309
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