Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein

VGLL4 is a transcriptional repressor that interacts with transcription factors TEADs and inhibits YAP-induced overgrowth and tumorigenesis. VGLL4 protein was dramatically reduced in various types of human cancers. But how VGLL4 protein is post-transcriptional regulated is poorly understood. In this...

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Bibliografske podrobnosti
izdano v:Am J Cancer Res
Main Authors: Zhang, Encheng, Shen, Bing, Mu, Xingyu, Qin, Yan, Zhang, Fang, Liu, Yong, Xiao, Jiantao, Zhang, Pingzhao, Wang, Chenji, Tan, Mingyue, Fan, Yu
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199763/
https://ncbi.nlm.nih.gov/pubmed/28042509
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