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Role of Cl(−)–HCO(3) (−) exchanger AE3 in intracellular pH homeostasis in cultured murine hippocampal neurons, and in crosstalk to adjacent astrocytes

KEY POINTS: A polymorphism of human AE3 is associated with idiopathic generalized epilepsy. Knockout of AE3 in mice lowers the threshold for triggering epileptic seizures. The explanations for these effects are elusive. Comparisons of cells from wild‐type vs. AE3(–/–) mice show that AE3 (present in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Physiol
मुख्य लेखकों: Salameh, Ahlam I., Hübner, Christian A., Boron, Walter F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199729/
https://ncbi.nlm.nih.gov/pubmed/27353306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272470
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