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Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?

Prader-Willi syndrome (PWS) is a complex disorder that manifests with an array of phenotypes, such as hypotonia and difficulties in feeding during infancy and reduced energy expenditure, hyperphagia, and developmental delays later in life. While the genetic cause has long been known, it is still not...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Polex-Wolf, Joseph, Yeo, Giles S.H., O’Rahilly, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199707/
https://ncbi.nlm.nih.gov/pubmed/27941250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91307
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