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Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?

Prader-Willi syndrome (PWS) is a complex disorder that manifests with an array of phenotypes, such as hypotonia and difficulties in feeding during infancy and reduced energy expenditure, hyperphagia, and developmental delays later in life. While the genetic cause has long been known, it is still not...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Polex-Wolf, Joseph, Yeo, Giles S.H., O’Rahilly, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199707/
https://ncbi.nlm.nih.gov/pubmed/27941250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91307
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