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Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?

Prader-Willi syndrome (PWS) is a complex disorder that manifests with an array of phenotypes, such as hypotonia and difficulties in feeding during infancy and reduced energy expenditure, hyperphagia, and developmental delays later in life. While the genetic cause has long been known, it is still not...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Polex-Wolf, Joseph, Yeo, Giles S.H., O’Rahilly, Stephen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199707/
https://ncbi.nlm.nih.gov/pubmed/27941250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91307
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