Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell

Activation of hepatic stellate cells (HSCs) is a pivotal event in liver fibrosis, characterized by dramatic disappearance of lipid droplets (LDs). Although LD disappearance has long been considered one of the hallmarks of HSC activation, the underlying molecular mechanisms are largely unknown. In th...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Zhang, Zili, Zhao, Shifeng, Yao, Zhen, Wang, Ling, Shao, Jiangjuan, Chen, Anping, Zhang, Feng, Zheng, Shizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199192/
https://ncbi.nlm.nih.gov/pubmed/28038427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.021
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