Metabolomic analysis identifies differentially produced oral metabolites, including the oncometabolite 2-hydroxyglutarate, in patients with head and neck squamous cell carcinoma

BACKGROUND: Metabolomics represents a promising approach for discovering novel targets and biomarkers in head and neck squamous cell carcinoma (HNSCC). Here we used metabolomics to identify oral metabolites associated with HNSCC. METHODS: Tumor and adjacent normal tissue from surgical resections and...

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Detalhes bibliográficos
Publicado no:BBA Clin
Main Authors: Mukherjee, Pranab K., Funchain, Pauline, Retuerto, Mauricio, Jurevic, Richard J., Fowler, Nicole, Burkey, Brian, Eng, Charis, Ghannoum, Mahmoud A
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199158/
https://ncbi.nlm.nih.gov/pubmed/28053877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2016.12.001
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