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Yeast GPCR signaling reflects the fraction of occupied receptors, not the number

According to receptor theory, the effect of a ligand depends on the amount of agonist–receptor complex. Therefore, changes in receptor abundance should have quantitative effects. However, the response to pheromone in Saccharomyces cerevisiae is robust (unaltered) to increases or reductions in the ab...

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Podrobná bibliografie
Vydáno v:Mol Syst Biol
Hlavní autoři: Bush, Alan, Vasen, Gustavo, Constantinou, Andreas, Dunayevich, Paula, Patop, Inés Lucía, Blaustein, Matías, Colman‐Lerner, Alejandro
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199120/
https://ncbi.nlm.nih.gov/pubmed/28034910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20166910
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