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A Model Based Cost-Effectiveness Analysis of Routine Genotyping for CYP2D6 among Older, Depressed Inpatients Starting Nortriptyline Pharmacotherapy

OBJECTIVE: Genotyping for CYP2D6 has the potential to predict differences in metabolism of nortriptyline. This information could optimize pharmacotherapy. We determined the costs and effects of routine genotyping for old aged Dutch depressed inpatients. METHODS: With a decision-tree, we modelled the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Berm, Elizabeth J. J., Gout-Zwart, Judith J., Luttjeboer, Jos, Wilffert, Bob, Postma, Maarten J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199075/
https://ncbi.nlm.nih.gov/pubmed/28033366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169065
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