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Effects of HIV/TAT protein expression and chronic selegiline treatment on spatial memory, reversal learning and neurotransmitter levels in mice

Neurotoxic viral protein TAT may contribute to deficits in dopaminergic and cognitive function in individuals infected with human immunodeficiency virus. Transgenic mice with brain-specific doxycycline-induced TAT expression (TAT+, TAT- control) show impaired cognition. However, previously reported...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Kesby, James P., Markou, Athina, Semenova, Svetlana
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198783/
https://ncbi.nlm.nih.gov/pubmed/27211061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.05.034
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