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MAP17 Is a Necessary Activator of Renal Na(+)/Glucose Cotransporter SGLT2
The renal proximal tubule reabsorbs 90% of the filtered glucose load through the Na(+)-coupled glucose transporter SGLT2, and specific inhibitors of SGLT2 are now available to patients with diabetes to increase urinary glucose excretion. Using expression cloning, we identified an accessory protein,...
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| Publicado no: | J Am Soc Nephrol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5198278/ https://ncbi.nlm.nih.gov/pubmed/27288013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015111282 |
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