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The Human Sodium-Glucose Cotransporter (hSGLT1) Is a Disulfide-Bridged Homodimer with a Re-Entrant C-Terminal Loop

Na-coupled cotransporters are proteins that use the trans-membrane electrochemical gradient of Na to activate the transport of a second solute. The sodium-glucose cotransporter 1 (SGLT1) constitutes a well-studied prototype of this transport mechanism but essential molecular characteristics, namely...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sasseville, Louis J., Morin, Michael, Coady, Michael J., Blunck, Rikard, Lapointe, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854415/
https://ncbi.nlm.nih.gov/pubmed/27137918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154589
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