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Applications of High-Throughput Sequencing for In Vitro Selection and Characterization of Aptamers
Aptamers are identified through an iterative process of evolutionary selection starting from a random pool containing billions of sequences. Simultaneously to the amplification of high-affinity candidates, the diversity in the pool is exponentially reduced after several rounds of in vitro selection....
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| Gepubliceerd in: | Pharmaceuticals (Basel) |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5198051/ https://ncbi.nlm.nih.gov/pubmed/27973417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph9040076 |
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