Knock out of the NADPH oxidase Nox4 has no impact on life span in mice

The free radical theory of aging suggests reactive oxygen species as a main reason for accumulation of damage events eventually leading to aging. Nox4, a member of the family of NADPH oxidases constitutively produces ROS and therefore has the potential to be a main driver of aging. Herein we analyze...

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Bibliografische gegevens
Gepubliceerd in:Redox Biol
Hoofdauteurs: Rezende, Flavia, Schürmann, Christoph, Schütz, Susanne, Harenkamp, Sabine, Herrmann, Eva, Seimetz, Michael, Weißmann, Norbert, Schröder, Katrin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5196091/
https://ncbi.nlm.nih.gov/pubmed/28038425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.012
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