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The regulatory B cell compartment expands transiently during childhood and is contracted in children with autoimmunity

OBJECTIVE: Regulatory B cells that inhibit immune responses through interleukin-10 (IL-10) secretion (B10 cells) have been characterized in adults with autoimmune disease. This study examines B10 cells across the entire age range of normal human development, and their changes during pediatric autoim...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Kalampokis, Ioannis, Venturi, Guglielmo M., Poe, Jonathan C., Dvergsten, Jeffrey A., Sleasman, John W., Tedder, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5195882/
https://ncbi.nlm.nih.gov/pubmed/27429419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39820
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