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Establishment of reporter lines for detecting fragile X mental retardation (FMR1) gene reactivation in human neural cells

Human patient-derived induced pluripotent stem cells (hiPSCs) provide unique opportunities for disease modeling and drug development. However, adapting hiPSCs or their differentiated progenies to high throughput assays for phenotyping or drug screening has been challenging. Fragile X syndrome (FXS)...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Li, Meng, Zhao, Huashan, Ananiev, Gene E., Musser, Michael, Ness, Kathryn H., Maglaque, Dianne L., Saha, Krishanu, Bhattacharyya, Anita, Zhao, Xinyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5195860/
https://ncbi.nlm.nih.gov/pubmed/27422057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2463
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