Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.

Human erythropoietin gene expression in liver and kidney is inducible by anemia or hypoxia. DNase I-hypersensitive sites were identified 3' to the human erythropoietin gene in liver nuclei. A 256-base-pair region of 3' flanking sequence was shown by DNase I protection and electrophoretic mobility-sh...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Semenza, G L, Nejfelt, M K, Chi, S M, Antonarakis, S E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5680
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