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Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.

Human erythropoietin gene expression in liver and kidney is inducible by anemia or hypoxia. DNase I-hypersensitive sites were identified 3' to the human erythropoietin gene in liver nuclei. A 256-base-pair region of 3' flanking sequence was shown by DNase I protection and electrophoretic m...

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Bibliografiska uppgifter
Huvudupphovsmän: Semenza, G L, Nejfelt, M K, Chi, S M, Antonarakis, S E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC51941/
https://ncbi.nlm.nih.gov/pubmed/2062846
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