Human Lin28 Forms a High-Affinity 1:1 Complex with the 106~363 Cluster miRNA miR-363

[Image: see text] Lin28A is a post-transcriptional regulator of gene expression that interacts with and negatively regulates the biogenesis of let-7 family miRNAs. Recent data suggested that Lin28A also binds the putative tumor suppressor miR-363, a member of the 106~363 cluster of miRNAs. Affinity...

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Publicat a:Biochemistry
Autors principals: Peters, Daniel T., Fung, Herman K. H., Levdikov, Vladimir M., Irmscher, Tobias, Warrander, Fiona C., Greive, Sandra J., Kovalevskiy, Oleg, Isaacs, Harry V., Coles, Mark, Antson, Alfred A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193468/
https://ncbi.nlm.nih.gov/pubmed/27559824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00682
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