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ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase

Inhibition of glycolysis is of great potential for the treatment of cancer. However, inhibitors of glycolytic enzymes with favorable pharmacological profiles have not been forthcoming. Due to the nature of their active sites, most high-affinity transition-state analogue inhibitors of glycolysis enzy...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Satani, Nikunj, Lin, Yu-Hsi, Hammoudi, Naima, Raghavan, Sudhir, Georgiou, Dimitra K., Muller, Florian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193436/
https://ncbi.nlm.nih.gov/pubmed/28030597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168739
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