Identification of Germline Genetic Mutations in Pancreatic Cancer Patients

BACKGROUND: Pancreatic adenocarcinoma (PAC) is part of several cancer predisposition syndromes; however, indications for genetic counseling/testing are not well-defined. We sought to determine mutation prevalence and characteristics that predict for inherited predisposition to PAC. METHODS: We ident...

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Publié dans:Cancer
Auteurs principaux: Salo-Mullen, Erin E., O’Reilly, Eileen, Kelsen, David, Ashraf, Asad M., Lowery, Maeve, Yu, Kenneth, Reidy, Diane, Epstein, Andrew S., Lincoln, Anne, Saldia, Amethyst, Jacobs, Lauren M., Rau-Murthy, Rohini, Zhang, Liying, Kurtz, Robert, Saltz, Leonard, Offit, Kenneth, Robson, Mark, Stadler, Zsofia K.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193099/
https://ncbi.nlm.nih.gov/pubmed/26440929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29664
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