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Absence of loss of heterozygosity of BRCA1 in a renal tumor from a BRCA1 germline mutation carrier

BRCA1 functions as a tumor suppressor gene and germline and somatic mutations in this gene have been shown to be associated with many types of cancer. We report the first tumor study of renal cell carcinoma in a carrier of the deleterious BRCA1 mutation-c.68_69delAG.

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Detalhes bibliográficos
Publicado no:Fam Cancer
Main Authors: Alanee, Shaheen, Shah, Sohela, Murali, Rajmohan, Rau-Murthy, Rohini, Schrader, Kasmintan A., Offit, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073794/
https://ncbi.nlm.nih.gov/pubmed/23086583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-012-9572-0
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