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Xanthohumol Modulates Calcium Signaling in Rat Ventricular Myocytes: Possible Antiarrhythmic Properties

Cardiac arrhythmia is a major cause of mortality in cardiovascular pathologies. A host of drugs targeted to sarcolemmal Na(+), Ca(2+), and K(+) channels has had limited success clinically. Recently, Ca(2+) signaling has been target of pharmacotherapy based on finding that leaky ryanodine receptors e...

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Bibliografiske detaljer
Udgivet i:J Pharmacol Exp Ther
Main Authors: Arnaiz-Cot, Juan Jose, Cleemann, Lars, Morad, Martin
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193078/
https://ncbi.nlm.nih.gov/pubmed/27815365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.236588
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