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Transcriptional Regulation of CYP2D6 Expression

CYP2D6-mediated drug metabolism exhibits large interindividual variability. Although genetic variations in the CYP2D6 gene are well known contributors to the variability, the sources of CYP2D6 variability in individuals of the same genotype remain unexplained. Accumulating data indicate that transcr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Metab Dispos
Hauptverfasser: Pan, Xian, Ning, Miaoran, Jeong, Hyunyoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193069/
https://ncbi.nlm.nih.gov/pubmed/27698228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.072249
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