Modeling Longitudinal Preclinical Tumor Size Data to Identify Transient Dynamics in Tumor Response to Antiangiogenic Drugs

Experimental evidence suggests that antiangiogenic therapy gives rise to a transient window of vessel normalization, within which the efficacy of radiotherapy and chemotherapy may be enhanced. Preclinical experiments that measure components of vessel normalization are invasive and expensive. We have...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Hutchinson, LG, Mueller, H‐J, Gaffney, EA, Maini, PK, Wagg, J, Phipps, A, Boetsch, C, Byrne, HM, Ribba, B
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192995/
https://ncbi.nlm.nih.gov/pubmed/27863175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12142
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