Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo‐electron microscopy

The tremendous pandemic potential of coronaviruses was demonstrated twice in the last 15 years by two global outbreaks of deadly pneumonia. Entry of coronaviruses into cells is mediated by the transmembrane spike glycoprotein S, which forms a trimer carrying receptor‐binding and membrane fusion func...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Walls, Alexandra, Tortorici, M. Alejandra, Bosch, Berend‐Jan, Frenz, Brandon, Rottier, Peter J. M., DiMaio, Frank, Rey, Felix A., Veesler, David
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192993/
https://ncbi.nlm.nih.gov/pubmed/27667334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3048
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