Antidepressant‐like effects of fenofibrate in mice via the hippocampal brain‐derived neurotrophic factor signalling pathway

BACKGROUND AND PURPOSE: Depression is a neuropsychiatric disorder accompanied by a decrease in the brain‐derived neurotrophic factor (BDNF) signalling cascade in the hippocampus. Fenofibrate is a selective agonist of PPAR‐α. In this study, we investigated the antidepressant‐like effects of fenofibra...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Jiang, Bo, Wang, Ying‐Jie, Wang, Hao, Song, Lu, Huang, Chao, Zhu, Qing, Wu, Feng, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192965/
https://ncbi.nlm.nih.gov/pubmed/27861729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13668
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