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Homologous Prime-Boost Vaccination with OVA Entrapped in Self-Adjuvanting Archaeosomes Induces High Numbers of OVA-Specific CD8(+) T Cells that Protect Against Subcutaneous B16-OVA Melanoma
Homologous prime-boost vaccinations with live vectors typically fail to induce repeated strong CD8(+) T cell responses due to the induction of anti-vector immunity, highlighting the need for alternative delivery vehicles. The unique ether lipids of archaea may be constituted into liposomes, archaeos...
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| Publicado no: | Vaccines (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5192364/ https://ncbi.nlm.nih.gov/pubmed/27869670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines4040044 |
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