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Homologous Prime-Boost Vaccination with OVA Entrapped in Self-Adjuvanting Archaeosomes Induces High Numbers of OVA-Specific CD8(+) T Cells that Protect Against Subcutaneous B16-OVA Melanoma

Homologous prime-boost vaccinations with live vectors typically fail to induce repeated strong CD8(+) T cell responses due to the induction of anti-vector immunity, highlighting the need for alternative delivery vehicles. The unique ether lipids of archaea may be constituted into liposomes, archaeos...

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Detaylı Bibliyografya
Yayımlandı:Vaccines (Basel)
Asıl Yazarlar: Stark, Felicity C., McCluskie, Michael J., Krishnan, Lakshmi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192364/
https://ncbi.nlm.nih.gov/pubmed/27869670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines4040044
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