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An Archaeosome-Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Significantly Enhances Protection from Murine Melanoma
Archaeosomes constitute archaeal lipid vesicle vaccine adjuvants that evoke a strong CD8(+) T cell response to antigenic cargo. Therapeutic treatment of murine B16-ovalbumin (B16-OVA) melanoma with archaeosome-OVA eliminates small subcutaneous solid tumors; however, they eventually resurge despite a...
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| Publié dans: | Vaccines (Basel) |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748605/ https://ncbi.nlm.nih.gov/pubmed/29072624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines5040038 |
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