Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice

Traumatic spinal cord injury (SCI) is followed by an instant increase in expression of the microglial-derived proinflammatory cytokine tumor necrosis factor (TNF) within the lesioned cord. TNF exists both as membrane-anchored TNF (mTNF) and as cleaved soluble TNF (solTNF). We previously demonstrated...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Ellman, Ditte Gry, Degn, Matilda, Lund, Minna Christiansen, Clausen, Bettina Hjelm, Novrup, Hans Gram, Flæng, Simon Bertram, Jørgensen, Louise Helskov, Suntharalingam, Lujitha, Svenningsen, Åsa Fex, Brambilla, Roberta, Lambertsen, Kate Lykke
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192339/
https://ncbi.nlm.nih.gov/pubmed/28070141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2684098
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