SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

We currently have limited knowledge of the involvement of long non-coding RNAs (lncRNAs) in normal cellular processes and pathologies. Here, we identify and characterize SNHG5 as a stable cytoplasmic lncRNA with up-regulated expression in colorectal cancer. Depletion of SNHG5 induces cell cycle arre...

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Detalhes bibliográficos
Publicado no:Nat Commun
Principais autores: Damas, Nkerorema Djodji, Marcatti, Michela, Côme, Christophe, Christensen, Lise Lotte, Nielsen, Morten Muhlig, Baumgartner, Roland, Gylling, Helene Maria, Maglieri, Giulia, Rundsten, Carsten Friis, Seemann, Stefan E., Rapin, Nicolas, Thézenas, Simon, Vang, Søren, Ørntoft, Torben, Andersen, Claus Lindbjerg, Pedersen, Jakob Skou, Lund, Anders H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192221/
https://ncbi.nlm.nih.gov/pubmed/28004750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13875
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