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Dosing and Pharmacokinetics of Polymyxin B in Patients with Renal Insufficiency

Polymyxin B remains the last-line treatment option for multidrug-resistant Gram-negative bacterial infections. Current U.S. Food and Drug Administration-approved prescribing information recommends that polymyxin B dosing should be adjusted according to the patient's renal function, despite stud...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Thamlikitkul, Visanu, Dubrovskaya, Yanina, Manchandani, Pooja, Ngamprasertchai, Thundon, Boonyasiri, Adhiratha, Babic, Jessica T., Tam, Vincent H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192162/
https://ncbi.nlm.nih.gov/pubmed/27799209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01337-16
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