PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages

The prolyl-4-hydroxylase domain (PHD) enzymes are regarded as the molecular oxygen sensors. There is an interplay between oxygen availability and cellular metabolism, which in turn has significant effects on the functionality of innate immune cells, such as macrophages. However, if and how PHD enzym...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Guentsch, Annemarie, Beneke, Angelika, Swain, Lija, Farhat, Katja, Nagarajan, Shunmugam, Wielockx, Ben, Raithatha, Kaamini, Dudek, Jan, Rehling, Peter, Zieseniss, Anke, Jatho, Aline, Chong, Mei, Santos, Celio X. C., Shah, Ajay M., Katschinski, Dörthe M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192080/
https://ncbi.nlm.nih.gov/pubmed/27795296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00236-16
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