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Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer

The role of Notch signaling in prostate cancer has not been defined definitively. Several large scale tissue microarray studies revealed that the expression of some Notch signaling components including the Jagged1 ligand are upregulated in advanced human prostate cancer specimens. Jagged1 expressed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Su, Qingtai, Zhang, Boyu, Zhang, Li, Dang, Truong, Rowley, David, Ittmann, Michael, Xin, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192002/
https://ncbi.nlm.nih.gov/pubmed/27345403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.232
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