Expansion induced microRNA changes in bone marrow mesenchymal stromal cells reveals interplay between immune regulation and cell cycle

Mesenchymal stromal cells (MSC) are currently used in many cell based therapies. Prior to use in therapy, extensive expansion is required. We used microarray profiling to investigate expansion induced miRNA and mRNA expression changes of bone marrow MSCs (BM-MSCs) derived from old and young donors....

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Kilpinen, Lotta, Parmar, Amarjit, Greco, Dario, Korhonen, Matti, Lehenkari, Petri, Saavalainen, Päivi, Laitinen, Saara
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191871/
https://ncbi.nlm.nih.gov/pubmed/27852979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101088
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