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A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): analysis of the retinoblastoma locus

Altered methylation patterns have been found to play a role in developmental disorders, cancer and aging. Increasingly, changes in DNA methylation are used as molecular markers of disease. Therefore, there is a need for reliable and easy to use techniques to detect and measure DNA methylation in res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Zeschnigk, Michael, Böhringer, Stefan, Price, Elizabeth Ann, Onadim, Zerrin, Maßhöfer, Lars, Lohmann, Dietmar R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC519124/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15353561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh122
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