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A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): analysis of the retinoblastoma locus

Altered methylation patterns have been found to play a role in developmental disorders, cancer and aging. Increasingly, changes in DNA methylation are used as molecular markers of disease. Therefore, there is a need for reliable and easy to use techniques to detect and measure DNA methylation in res...

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Autors principals: Zeschnigk, Michael, Böhringer, Stefan, Price, Elizabeth Ann, Onadim, Zerrin, Maßhöfer, Lars, Lohmann, Dietmar R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC519124/
https://ncbi.nlm.nih.gov/pubmed/15353561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh122
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