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An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene
We studied the mechanism by which an insulator interrupts enhancer signaling to a gene using stably replicated chromatin templates containing the human β-globin locus control region HS2 enhancer and a target globin gene. The chicken β-globin 5′ HS4 (cHS4) insulator acted as a positional enhancer blo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC519119/ https://ncbi.nlm.nih.gov/pubmed/15371553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh832 |
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