Polyadenylation-dependent screening assay for respiratory syncytial virus RNA transcriptase activity and identification of an inhibitor

RNA-dependent RNA polymerase from respiratory syncytial virus (RSV) is a multi-subunit ribonucleoprotein (RNP) complex that, in addition to synthesizing the full 15 222 nt viral genomic RNA, is able to synthesize all 10 viral mRNAs. We have prepared crude RNP from RSV-infected HEp-2 cells, based on...

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Hlavní autoři: Mason, Stephen W., Lawetz, Carol, Gaudette, Yvon, Dô, Florence, Scouten, Erika, Lagacé, Lisette, Simoneau, Bruno, Liuzzi, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC519107/
https://ncbi.nlm.nih.gov/pubmed/15356293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh809
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