Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in infants, immunocompromised patients, and the elderly. New antiviral agents would be important tools in the treatment of acute RSV disease. RSV encodes its own RNA-dependent RNA polymerase that is responsible for the synthes...

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Bibliographic Details
Main Authors: Liuzzi, Michel, Mason, Stephen W., Cartier, Mireille, Lawetz, Carol, McCollum, Robert S., Dansereau, Nathalie, Bolger, Gordon, Lapeyre, Nicole, Gaudette, Yvon, Lagacé, Lisette, Massariol, Marie-Josée, Dô, Florence, Whitehead, Paul, Lamarre, Lyne, Scouten, Erika, Bordeleau, Josée, Landry, Serge, Rancourt, Jean, Fazal, Gulrez, Simoneau, Bruno
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235819/
https://ncbi.nlm.nih.gov/pubmed/16189012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.13105-13115.2005
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