Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in infants, immunocompromised patients, and the elderly. New antiviral agents would be important tools in the treatment of acute RSV disease. RSV encodes its own RNA-dependent RNA polymerase that is responsible for the synthes...

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Detalhes bibliográficos
Main Authors: Liuzzi, Michel, Mason, Stephen W., Cartier, Mireille, Lawetz, Carol, McCollum, Robert S., Dansereau, Nathalie, Bolger, Gordon, Lapeyre, Nicole, Gaudette, Yvon, Lagacé, Lisette, Massariol, Marie-Josée, Dô, Florence, Whitehead, Paul, Lamarre, Lyne, Scouten, Erika, Bordeleau, Josée, Landry, Serge, Rancourt, Jean, Fazal, Gulrez, Simoneau, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235819/
https://ncbi.nlm.nih.gov/pubmed/16189012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.13105-13115.2005
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