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Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in infants, immunocompromised patients, and the elderly. New antiviral agents would be important tools in the treatment of acute RSV disease. RSV encodes its own RNA-dependent RNA polymerase that is responsible for the synthes...

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Détails bibliographiques
Auteurs principaux: Liuzzi, Michel, Mason, Stephen W., Cartier, Mireille, Lawetz, Carol, McCollum, Robert S., Dansereau, Nathalie, Bolger, Gordon, Lapeyre, Nicole, Gaudette, Yvon, Lagacé, Lisette, Massariol, Marie-Josée, Dô, Florence, Whitehead, Paul, Lamarre, Lyne, Scouten, Erika, Bordeleau, Josée, Landry, Serge, Rancourt, Jean, Fazal, Gulrez, Simoneau, Bruno
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235819/
https://ncbi.nlm.nih.gov/pubmed/16189012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.13105-13115.2005
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