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SKN-1-independent transcriptional activation of glutathione S-transferase 4 (GST-4) by EGF signaling

In C. elegans research, transcriptional activation of glutathione S-transferase 4 (gst-4) is often used as a read-out for SKN-1 activity. While many heed an assumed non-exclusivity of the GFP reporter signal driven by the gst-4 promoter to SKN-1, this is also often ignored. We here show that gst-4 c...

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Publicado en:Worm
Main Authors: Detienne, Giel, Van de Walle, Pieter, De Haes, Wouter, Schoofs, Liliane, Temmerman, Liesbet
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190145/
https://ncbi.nlm.nih.gov/pubmed/28090393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21624054.2016.1230585
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