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Molecular driver alterations and their clinical relevance in cancer of unknown primary site

Cancer of unknown primary (CUP) is defined as metastatic solid malignancy where no primary tumor is detected despite appropriate staging. About 90% of CUP represent adenocarcinoma or undifferentiated carcinoma. Since therapy regimens are only modestly effective, identification of the molecular lands...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Löffler, Harald, Pfarr, Nicole, Kriegsmann, Mark, Endris, Volker, Hielscher, Thomas, Lohneis, Philipp, Folprecht, Gunnar, Stenzinger, Albrecht, Dietel, Manfred, Weichert, Wilko, Krämer, Alwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190099/
https://ncbi.nlm.nih.gov/pubmed/27322425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10035
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