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E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells

Substantial experimental evidence has shown that dedifferentiation from an epithelial state to a mesenchymal-like state (EMT) drives tumor cell metastasis. This transition facilitates tumor cells to acquire motility and invasive features. Intriguingly, tumor cells at the metastatic site are primaril...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Palen, Katie, Weber, James, Dwinell, Michael B., Johnson, Bryon D., Ramchandran, Ramani, Gershan, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190029/
https://ncbi.nlm.nih.gov/pubmed/27270319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9715
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