Protein inhibitor of activated STAT 4 (PIAS4) regulates pro-inflammatory transcription in hepatocytes by repressing SIRT1

Excessive nutrition promotes the pathogenesis of non-alcoholic steatohepatitis (NASH), characterized by the accumulation of pro-inflammation mediators in the liver. In the present study we investigated the regulation of pro-inflammatory transcription in hepatocytes by protein inhibitor of activated...

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Pubblicato in:Oncotarget
Autori principali: Sun, Lina, Fan, Zhiwen, Chen, Junliang, Tian, Wenfang, Li, Min, Xu, Huihui, Wu, Xiaoyan, Fang, Mingming, Xia, Jun, Xu, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper: Pathology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189995/
https://ncbi.nlm.nih.gov/pubmed/27285989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9864
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