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In situ analysis of repair processes for oxidative DNA damage in mammalian cells

Oxidative DNA damage causes blocks and errors in transcription and replication, leading to cell death and genomic instability. Although repair mechanisms of the damage have been extensively analyzed in vitro, the actual in vivo repair processes remain largely unknown. Here, by irradiation with an UV...

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Detalhes bibliográficos
Main Authors: Lan, Li, Nakajima, Satoshi, Oohata, Yoshitsugu, Takao, Masashi, Okano, Satoshi, Masutani, Mitsuko, Wilson, Samuel H., Yasui, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518826/
https://ncbi.nlm.nih.gov/pubmed/15365186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406048101
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