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Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage

Nitric oxide (NO(•)) is thought to protect against the damaging effects of myocardial ischemia–reperfusion injury, whereas xanthine oxidoreductase (XOR) normally causes damage through the generation of reactive oxygen species. In the heart, inorganic nitrite [Formula: see text] has the potential to...

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Detalhes bibliográficos
Main Authors: Webb, Andrew, Bond, Richard, McLean, Peter, Uppal, Rakesh, Benjamin, Nigel, Ahluwalia, Amrita
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518813/
https://ncbi.nlm.nih.gov/pubmed/15347817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402927101
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